Defenders of Ardania runs but very slow, not playable, see down for more info.
Simpsons run great.

Defenders of Ardania

Cannot go lower than 1280x720, even editing configuration files doesn't help.
Everything on low with 1280x720 goes in 3-8 FPS, very slow and not playable.

You can force game to 640x480
(right-click game exe and Properties, under Compatibility select
Run in 640x480 screen resolution)
but game is not optimized for that resolution so it is just going to cut half of the ingame screen.
You get more FPS 9-18 and it runs smooth but you can't see anything.

Example screenshots for 640x480:
Low Resolution SCREENSHOT 1
Low Resolution SCREENSHOT 2
Low Resolution SCREENSHOT 3

Screenshots:
SCREENSHOT 1
SCREENSHOT 2
SCREENSHOT 3
SCREENSHOT 4

The Simpsons: Hit & Run

Running great, in 20-30 FPS
Highest possible resolution for my laptop was 1024x768, 4:3.
But with external display it plays great with bigger resolutions.

Screenshots:
SCREENSHOT 1
SCREENSHOT 2
SCREENSHOT 3
SCREENSHOT 4